Novartis kandidat visar signifikant effekt mot autoimmun sjukdom

Novartis rapporterar positiva resultat för sin läkemedelskandidat ianalumab, som prövats i en sen klinisk fas som behandling för den autoimmuna systemsjukdomen Sjögrens syndrom.

By Ella Käck

August 11, 2025 7:55 AM

I två fas III-studier, NEPTUNUS-1 och NEPTUNUS-2, uppnådde ianalumab sina primära mål. Behandlingen visade en statistiskt signifikant minskning av sjukdomsaktiviteten, enligt den schweiziska läkemedelsjätten Novartis.

Ianalumab är en experimentell antikroppsbehandling som angriper B-celler genom att blockera ett protein kallat BAFF-R. Syftet är att dämpa överaktivitet i immunsystemet vid autoimmuna sjukdomar.

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