Bolt halverar personalstyrkan när studieresultat försenas

Det amerikanska bioteknikbolaget Bolt Biotherapeutics genomför ännu en stor nedskärning. För andra gången på två år halveras personalstyrkan, i ett försök att frigöra resurser till bolagets pågående satsning på avancerad immunterapi.

By Ella Käck

October 3, 2025 10:45 AM

Bolt Biotherapeutics har det senaste året fokuserat på att utveckla läkemedelskandidaten BDC-4812, ett immunstimulerande antikroppskonjugat, som riktar sig mot proteinet Claudin 18.2. Detta protein är kopplat till vissa former av magsäckscancer och cancer i övergången mellan matstrupe och magsäck.

Under första halvåret 2026 hade Bolt planerat att presentera preliminära resultat från en fas I-studie med BDC-4812. Men så blir inte fallet.

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