Ny generation CAR-T testas i Sverige – ska utvärderas vid reumatisk sjukdom

CAR-T-terapier har på drygt ett decennium gått från experimentell cancerbehandling till etablerad del av vården. Nu tar behandlingen ett nytt kliv i Sverige, när den för första gången ska prövas vid den reumatiska sjukdomen SLE.

By Lotta Naesenius

March 13, 2026 8:01 AM

I slutet av februari inleddes en klinisk prövning vid Akademiska sjukhuset och Karolinska universitetssjukhuset där CD19-riktad CAR-T-cellterapi för första gången i landet ska utvärderas vid den autoimmuna sjukdomen systemisk lupus erythematosus (SLE).

SLE är en kronisk, autoimmun sjukdom som till 90 procent drabbar kvinnor. Trots flera nya godkända läkemedel under senare år finns en grupp patienter med kvarstående hög sjukdomsaktivitet och risk för organskador.

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