Ny typ av ADC:er ska binda bättre till målet

Regeneron ingår ett samarbete med biotechbolaget Parabilis Medicines för att utveckla en ny typ av antikroppsläkemedelskonjugat (ADC) med förbättrad förmåga att binda till svåråtkomliga mål.

By Anders Göransson

May 19, 2026 11:29 AM

ADC‑fältet växer snabbt, men många läkemedelskandidater faller på att antikroppen inte binder till målproteinet tillräckligt bra.

Parabilis försöker lösa det problemet med konjugat baserade på Helicon-peptider (AHC), som designats för att kunna ta sig in i celler och binda till platta ytor på proteiner, som vanliga små molekyler ofta inte kan fästa vid.

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