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Athera signs production partnership

The companys novel cardiovascular product will be manufactured in Germany.
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The german biotechnology company

Richter-Helm Biologics and Swedish Athera Biotechnologies have signed an agreement for the development and manufacturing of Athera's novel product, Annexin A5. It is a recombinant protein developed to prevent plaque rupture and athero-thrombosis through binding to endothelium. The protein is intended for the treatment of patients with Acute Coronary Syndrome, at imminent risk for Myocardial Infarction.

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This agreement secures

what Athera describes as a very cost efficient long-term development and manufacturing plan for the company, and may include future large volume commercial production. The production process will be based on Richter-Helm's proprietary E. coli based expression system. Richter-Helm will initiate strain and process development of the new process, reaching a 1,000 litre production scale.

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"We are very pleased

to get Richter-Helm as our development partner, they have an excellent reputation. We have now secured a cost competitive and high quality production for clinical and commercial use", says Carina Schmidt, CEO of Athera Biotechnologies.

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This is the second pa

rtnership for Athera over the last few months. Early October last year the company announced a collaboration with Dyax Corp. to discover and develop antibodies for treatment of cardiovascular inflammation.

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